前聯合國調查員傑瑞·藍恩(Gerry Lane)帶着妻子凱倫和兩個女兒在費城市區公路上行車時,首先注意到多架直升機從空中飛過,電臺新聞上一直在談論狂犬病。這時,公路前方發生爆炸,連路上執勤的警察都當場被失控的垃圾車撞死,傑瑞本想離開公路卻與一輛失控的救護車相撞,一家人回過神來後立即棄車逃跑。城市廣場上出現幾百名瘋狂咬人的殭屍,傑瑞還目睹一名被殭...
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