在歐洲鄉間的祕密研究室裡, 一位頂尖的科學家正對著兩隻巨蟒進行實驗測試. 當資助者(約翰萊斯戴維斯飾) 企圖干預實驗時, 飢餓的蟒蛇逃出了研究室. 漢密特(戴維赫索霍夫飾) 受僱追捕牠們, 其任務是必須在蟒蛇竄逃到城市且在災難擴大以前, 實時捉拿這多產又極度致命的生物……
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